Absolute configurations of talaromycones A and B, α-diversonolic ester, and aspergillusone B from endophytic Talaromyces sp. ECN211

• Ken-ichi Nakashima,
• Junko Tomida,
• Takao Hirai,
• Yoshiaki Kawamura and
• Makoto Inoue

Beilstein J. Org. Chem. 2020, 16, 290–296, doi:10.3762/bjoc.16.28

• -cho, Chikusa-ku, Nagoya, Aichi, Japan 10.3762/bjoc.16.28 Abstract Talaromycones A (1) and B (2), new xanthenediones, were isolated from the cultures of Talaromyces sp. ECN211, an endophytic fungus, along with α-diversonolic ester (3), aspergillusone B (4), glauconic acid (5), and rosellisin (6). The

• first time in over 50 years. Keywords: absolute configuration; endophytic fungus; glauconic acid; Talaromyces; tetrahydroxanthone; xanthenedione; Introduction The xanthones, which are a class of phenolic compounds produced by many different organisms, including plants, lichens, fungi, and bacteria

• determination of the absolute configuration of 1–4 by single-crystal X-ray diffraction and ECD spectroscopy. In addition, we also updated the crystallographic data for glauconic acid (5), a known nonadride. Results and Discussion Talaromyces sp. ECN211 was isolated from healthy leaves of Selaginella tamariscana